Dried Protein & Stability Blocking
Gold standard
Surmodics immunoassay reagents preserve the conformation and activity of dried proteins coated on a wide range of surfaces, keeping antibodies and antigens at peak performance for long durations. At the same time, the blocking mechanisms in these reagents reduce non-specific binding of interfering proteins to maximize assay sensitivity.
Our immunoassay stabilizers are the gold standard for stability and blocking efficacy. They provide improved assay performance in a one-step process for streamlined manufacturing.
Shop All ProductsSignal-to-noise ratios
StabilMaX™, StabilCoat™, StabilGuard™ and StabilBlock™ Immunoassay Stabilizers provide alternative blocking mechanisms to achieve the best signal-to-noise ratios for each assay.
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Boosting sensitivity. Surmodics Immunoassay Stabilizers provide a choice of blocking mechanisms to achieve optimal signal-to-noise ratios for each assay.
Top standards were run on a rabbit polyclonal IgG ELISA using plates blocked with StabilMaX™, StabilBlock™, StabilCoat™, StabilGuard™ Immunoassay Stabilizers and a competitive commercial blocker. The signal-to-noise rations were quantified.
Shop NowSurmodics Immunoassay Stabilizers give assay developers the best possible tools to lower non-specific binding and maximize the signal-to-noise ratios of assays.
Learn more about protein stabilizers
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Differentiated blocking. Assay developers often need to evaluate numerous blocking mechanisms during protocol development and optimization. Surmodics Immunoassay Stabilizers provide a variety of blocking mechanisms to achieve the best signal-to-noise ratios for each assay.
Blocking Strength
Dried Protein Stability
Surmodics Immunoassay Stabilizers provide exceptional preservation of the activity of dried proteins.
Learn more about how to determine protein stabilityShop Now
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Prolonging shelf life. Accelerated stability projections demonstrate significant retained activity of dried proteins with Surmodics Immunoassay Stabilizers
The accelerated stability tests used a rabbit polyclonal IgG ELISA assay to assess each stabilizer. 69 days of accelerated stability testing is equivalent to just under 2 years of real-time stability.
Longer stability
- Extended shelf life of dried proteins on various surfaces, including polystyrene plates, latex beads, magnetic particles and nitrocellulose membranes
Increased sensitivity
- Increased signal-to-noise ratios across the assay range
- Multiple formulations to optimize detection limits
Negligible backgrounds
- Elimination of non-specific binding from the sample matrix and other assay components
Ease of manufacture
- One-step blocking and stabilization process for shorter cycle times
- ISO 13485/9001 facility for lot-to-lot consistency
SX01 - StabilMaX™ Immunoassay Stabilizer
StabilMaX™ Immunoassay stabilizer maintains assay signal and provides stability with ample blocking capability to reduce non-specific binding, often ideal for antigen-down assays.
SC01 - StabilCoat™ Immunoassay Stabilizer
StabilCoat™ Immunoassay Stabilizer increases signal-to-noise ratios of assays through effective blocking of the plate while maximizing the binding capacity of the antigen/antibody epitopes.
SC02 - StabilCoat™ Plus Stabilizer
StabilCoat™ Plus microarray stabilizer improves the stability of proteins covalently bound to microspheres stored in solution and array proteins stored in the dried state.
SC05 - 5X StabilCoat™ Immunoassay Stabilizer
5X StabilCoat™ Immunoassay Stabilizers increase signal-to-noise ratios of assays through effective blocking of the plate while maximizing the binding capacity of the antigen/antibody epitopes.
SG01 - StabilGuard™ Immunoassay Stabilizer
StabilGuard™ (BSA free) Immunoassay Stabilizers increase signal-to-noise ratios of assays through effective blocking of the plate while maximizing the binding capacity of the antigen/antibody epitopes.
SG02 - StabilGuard™ Choice Stabilizer
StabilGuard™ Choice Microarray Stabilizer (BSA-Free) improves the stability of proteins covalently bound to microspheres stored in solution and array proteins stored in the dried state, without the use of BSA protein.
ST01 - StabilBlock™ Immunoassay Stabilizer
StabilBlock™ Immunoassay Stabilizer gives assay developers the best possible tool to lower non-specific binding and maximize the signal-to-noise ratios of immunoassays.