Dried Protein & Stability Blocking

Gold standard

Surmodics immunoassay reagents preserve the conformation and activity of dried proteins coated on a wide range of surfaces, keeping antibodies and antigens at peak performance for long durations. At the same time, the blocking mechanisms in these reagents reduce non-specific binding of interfering proteins to maximize assay sensitivity.

Our immunoassay stabilizers are the gold standard for stability and blocking efficacy. They provide improved assay performance in a one-step process for streamlined manufacturing.

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Signal-to-noise ratios

StabilMaX™, StabilCoat™, StabilGuard™ and StabilBlock™ Immunoassay Stabilizers provide alternative blocking mechanisms to achieve the best signal-to-noise ratios for each assay.

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Boosting sensitivity. Surmodics Immunoassay Stabilizers provide a choice of blocking mechanisms to achieve optimal signal-to-noise ratios for each assay.

Top standards were run on a rabbit polyclonal IgG ELISA using plates blocked with StabilMaX™, StabilBlock™, StabilCoat™, StabilGuard™ Immunoassay Stabilizers and a competitive commercial blocker. The signal-to-noise rations were quantified.

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Surmodics Immunoassay Stabilizers give assay developers the best possible tools to lower non-specific binding and maximize the signal-to-noise ratios of assays.

Learn more about protein stabilizers

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Differentiated blocking. Assay developers often need to evaluate numerous blocking mechanisms during protocol development and optimization. Surmodics Immunoassay Stabilizers provide a variety of blocking mechanisms to achieve the best signal-to-noise ratios for each assay.

Blocking Strength

Dried Protein Stability

Surmodics Immunoassay Stabilizers provide exceptional preservation of the activity of dried proteins. 

Learn more about how to determine protein stability

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Prolonging shelf life. Accelerated stability projections demonstrate significant retained activity of dried proteins with Surmodics Immunoassay Stabilizers

The accelerated stability tests used a rabbit polyclonal IgG ELISA assay to assess each stabilizer. 69 days of accelerated stability testing is equivalent to just under 2 years of real-time stability.

Longer stability

  • Extended shelf life of dried proteins on various surfaces, including polystyrene plates, latex beads, magnetic particles and nitrocellulose membranes

Increased sensitivity

  • Increased signal-to-noise ratios across the assay range
  • Multiple formulations to optimize detection limits

Negligible backgrounds

  • Elimination of non-specific binding from the sample matrix and other assay components

Ease of manufacture

  • One-step blocking and stabilization process for shorter cycle times
  • ISO 13485/9001 facility for lot-to-lot consistency
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SG02 - StabilGuard™ Choice Stabilizer

StabilGuard™ Choice Microarray Stabilizer (BSA-Free) improves the stability of proteins covalently bound to microspheres stored in solution and array proteins stored in the dried state, without the use of BSA protein.

From $40.00/EA
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SG01 - StabilGuard™ Immunoassay Stabilizer

StabilGuard™ (BSA free) Immunoassay Stabilizers increase signal-to-noise ratios of assays through effective blocking of the plate while maximizing the binding capacity of the antigen/antibody epitopes.

From $40.00/EA
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SC01 - StabilCoat™ Immunoassay Stabilizer

StabilCoat™ Immunoassay Stabilizer increases signal-to-noise ratios of assays through effective blocking of the plate while maximizing the binding capacity of the antigen/antibody epitopes.

From $40.00/EA
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SC02 - StabilCoat™ Plus Stabilizer

StabilCoat™ Plus microarray stabilizer improves the stability of proteins covalently bound to microspheres stored in solution and array proteins stored in the dried state.

From $40.00/EA
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ST01 - StabilBlock™ Immunoassay Stabilizer

StabilBlock™ Immunoassay Stabilizer gives assay developers the best possible tool to lower non-specific binding and maximize the signal-to-noise ratios of immunoassays.

From $40.00/EA
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SX01 - StabilMaX™ Immunoassay Stabilizer

StabilMaX™ Immunoassay stabilizer maintains assay signal and provides stability with ample blocking capability to reduce non-specific binding, often ideal for antigen-down assays.

From $40.00/EA
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SC05 - 5X StabilCoat™ Immunoassay Stabilizer

5X StabilCoat™ Immunoassay Stabilizers increase signal-to-noise ratios of assays through effective blocking of the plate while maximizing the binding capacity of the antigen/antibody epitopes.

From $200.00/EA
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