Protein & Conjugate Stabilizers
unparalleled long-term stability
The Surmodics StabilZyme® family provides unparalleled long-term stability of protein conjugates at working strength concentrations for immunoassay development. Our formulations for HRP conjugates, AP conjugates and general protein applications ensure that assay developers have a complete set of tools to address the labile nature of each protein of interest.
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HRP Conjugate Stability (>2 years)
StabilZyme® HRP, StabilZyme® Protein-Free and StabilZyme® NOBLE stabilizers provide the assay developer a complete set of tools to stabilize different HRP conjugates for long term, in-solution stability.
Outstanding retained activity. Accelerated stability projections demonstrate at least 85% retained activity for greater than 2 years using StabilZyme® HRP and StabilZyme® Protein-Free Stabilizers.
The accelerated stability tests used horseradish peroxidase conjugates diluted in each stabilizer. 81 days of accelerated stability testing is equivalent to 2+ years of real-time stability.
StabilZyme® SELECT stabilizer is a general purpose in-solution protein stabilizer that can be used for HRP conjugates, standards and controls in immunoassay applications.
Superior real-time stability. A monoclonal IgG-HRP conjugate demonstrates over 90% retained activity with StabilZyme® HRP Stabilizer and over 75% retained activity with StabilZyme® SELECT Stabilizer.
The real-time stability tests used a monoclonal IgG- horseradish peroxidase conjugate diluted in each stabilizer and stored at room temperature for 2 years.
HRP Conjugate Stability (2 years)
AP Conjugate Stability
StabilZyme® AP and StabilZyme® Protein-Free AP stabilizers provide assay developers a complete set of tools to stabilize different AP conjugates for long term, in-solution stability.
Outstanding retained activity for AP. Accelerated stability projections demonstrate at least 80% retained activity for greater than 1.5 years using StabilZyme® AP and StabilZyme® Protein-Free AP Stabilizers.
The accelerated stability tests used monoclonal and polyclonal antibody-alkaline phosphatase conjugates diluted in each stabilizer. 56 days of accelerated stability testing is equivalent to 1.5+ years of real-time stability.
- Extended shelf life of antibodies, antigens and other proteins at working strength concentrations
- Retained activity of enzymes in solution for up to two years
- Multiple formulations with different stabilizing mechanisms to satisfy different enzyme/protein requirements
- Protein-free and BSA-free formulations are available to satisfy the background requirements for specific assay systems
- Stabilizes enzymes and control materials in ELISA/EIA, ELISpot, RIA, immunoblots and microarrays applications
Ease of manufacture
- Incorporates easily into assay production protocols to reduce costs and cycle times
- ISO 13485/9001 facility for lot-to-lot consistency
StabilZyme® AP Stabilizer specifically optimizes the AP enzyme and is the gold standard for in-solution conjugate stability.
StabilZyme® Protein-Free AP Stabilizer eliminates interference and cross-reactivity caused by proteins, delivering optimal performance for even the most sensitive immunoassays.
StabilZyme® HRP Conjugate Stabilizer is specifically optimized for the HRP enzyme and is the gold standard for in-solution conjugate stability.
StabilZyme® SELECT Stabilizer is a general purpose in-solution protein stabilizer that can be used for HRP conjugates, standards and controls in immunoassay applications.
StabilZyme® NOBLE Stabilizer eliminates protein interference and cross-reactivity that can result from the use of BSA in an assay system.