Protein & Conjugate Stabilizers

unparalleled long-term stability

The Surmodics StabilZyme® family provides unparalleled long-term stability of protein conjugates at working strength concentrations for immunoassay development. Our formulations for HRP conjugates, AP conjugates and general protein applications ensure that assay developers have a complete set of tools to address the labile nature of each protein of interest.

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HRP Conjugate Stability (>2 years)

StabilZyme® HRP, StabilZyme® Protein-Free and StabilZyme® NOBLE stabilizers provide the assay developer a complete set of tools to stabilize different HRP conjugates for long term, in-solution stability.

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Outstanding retained activity. Accelerated stability projections demonstrate at least 85% retained activity for greater than 2 years using StabilZyme® HRP and StabilZyme® Protein-Free Stabilizers.

The accelerated stability tests used horseradish peroxidase conjugates diluted in each stabilizer. 81 days of accelerated stability testing is equivalent to 2+ years of real-time stability.

StabilZyme® SELECT stabilizer is a general purpose in-solution protein stabilizer that can be used for HRP conjugates, standards and controls in immunoassay applications.

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Superior real-time stability. A monoclonal IgG-HRP conjugate demonstrates over 90% retained activity with StabilZyme® HRP Stabilizer and over 75% retained activity with StabilZyme® SELECT Stabilizer.

The real-time stability tests used a monoclonal IgG- horseradish peroxidase conjugate diluted in each stabilizer and stored at room temperature for 2 years.

HRP Conjugate Stability (2 years)

AP Conjugate Stability

StabilZyme® AP and StabilZyme® Protein-Free AP stabilizers provide assay developers a complete set of tools to stabilize different AP conjugates for long term, in-solution stability.

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Outstanding retained activity for AP. Accelerated stability projections demonstrate at least 80% retained activity for greater than 1.5 years using StabilZyme® AP and StabilZyme® Protein-Free AP Stabilizers.

The accelerated stability tests used monoclonal and polyclonal antibody-alkaline phosphatase conjugates diluted in each stabilizer. 56 days of accelerated stability testing is equivalent to 1.5+ years of real-time stability.

Longer stability

  • Extended shelf life of antibodies, antigens and other proteins at working strength concentrations
  • Retained activity of enzymes in solution for up to two years

Assay compatibility

  • Multiple formulations with different stabilizing mechanisms to satisfy different enzyme/protein requirements
  • Protein-free and BSA-free formulations are available to satisfy the background requirements for specific assay systems
  • Stabilizes enzymes and control materials in ELISA/EIA, ELISpot, RIA, immunoblots and microarrays applications

Ease of manufacture

  • Incorporates easily into assay production protocols to reduce costs and cycle times
  • ISO 13485/9001 facility for lot-to-lot consistency
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SA01 - StabilZyme® AP Conjugate stabilizer

StabilZyme® AP Stabilizer specifically optimizes the AP enzyme and is the gold standard for in-solution conjugate stability.

From $34.00/EA
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SAPF - StabilZyme® Protein-Free AP Stabilizer

StabilZyme® Protein-Free AP Stabilizer eliminates interference and cross-reactivity caused by proteins, delivering optimal performance for even the most sensitive immunoassays.

From $36.00/EA
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SZ02 - STABILZYME HRP

StabilZyme® HRP Conjugate Stabilizer is specifically optimized for the HRP enzyme and is the gold standard for in-solution conjugate stability.

From $34.00/EA
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SZ03 - STABILZYME SELECT

StabilZyme® SELECT Stabilizer is a general purpose in-solution protein stabilizer that can be used for HRP conjugates, standards and controls in immunoassay applications.

From $34.00/EA
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SZ04 - StabilZyme® Noble Stabilizer

StabilZyme® NOBLE Stabilizer eliminates protein interference and cross-reactivity that can result from the use of BSA in an assay system.

From $34.00/EA
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SZPF - StabilZyme® Protein-Free Stabilizer

StabilZyme® Protein-Free Stabilizer eliminates interference and cross-reactivity caused by proteins, delivering optimal performance for even the most sensitive immunoassays.

From $36.00/EA
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