TIF1 gamma

Transcriptional intermediary factor 1-gamma (TIF1 gamma), originally named p155 and synonymous for p155/140 and TRIM33, is a nuclear protein that functions as a mono-ubiquitin ligase for Smad4, a TGF-β signal transducer, leading to its inactivation. Consequently, the TGF-β signaling pathway, a major pathway for control of cell growth and differentiation, is downregulated. DIARECT™ antigens are for further manufacturing or research use only.

Origin
Recombinant. Expressed by recombinant baculovirus (Autographa californica multiple nuclear polyhedrosis virus; AcMNPV) infection of Spodoptera frugiperda Sf9 insect cells.
Biochemical Test
SDS-PAGE (purity > 80%); Western blot with i: anti-TIF1 gamma autoantibody-positive sera; ii: monoclonal anti-His-tag antibody.
Calculated Molecular Weight
124,041 Dalton
Calculated Isoelectric Point
pH 6.38

A110


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Option Quantity Unit Purchase
TIF1 GAMMA
A11000
0.1 mg
$130.00/EA
In Stock
TIF1 GAMMA
A11001
1.0 mg
$1,505.00/EA
In Stock

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