SmD3

In eukaryotic cells, the Sm-proteins B/B', D1, D2, D3, E, F, and G form a heteroheptameric protein core shared between all uracil-rich small nuclear ribonucleoprotein (U-snRNP) complexes. Like native SmD3, DIARECT's recombinant SmD3 contains symmetrically dimethylated arginine residues. DIARECT™ antigens are for further manufacturing or research use only.

Origin
Recombinant. Expressed by recombinant baculovirus (Autographa californica multiple nuclear polyhedrosis virus; AcMNPV) infection of Spodoptera frugiperda Sf9 insect cells. Expression conditions allow for introduction of symmetrical arginine dimethylation, thereby creating the main SmD3 autoepitope.
Biochemical Test
SDS-PAGE (purity > 80%); Western  blot with anti-Sm autoantibody-positive sera.
Calculated Molecular Weight
14,739 Dalton 
Calculated Isoelectric Point
pH 10.33
Coating Concentration
0.4-0.8 µg/ml (depending on the type of ELISA plate and coating buffer). Suitable for labeling of functional groups.

A120


Filter
Option Quantity Unit Purchase
SmD3
A12000
50 μg
$140.00/EA
In Stock
SmD3
A12001
1.0 mg
$1,595.00/EA
In Stock

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