PM/Scl 100

The polymyositis/scleroderma (PM/Scl) complex is the human ortholog of the Saccharomyces cerevisiae exosome, which is involved in the processing and degradation of RNAs. PM/Scl 100 is one of the human subunits found in the nucleoplasm and, at higher concentrations, in the nucleolus. DIARECT™ antigens are for further manufacturing or research use only.

Origin
Recombinant. Expressed by recombinant baculovirus (Autographa californica multiple nuclear polyhedrosis virus; AcMNPV) infection of Spodoptera frugiperda Sf9 insect cells.
Biochemical Test
SDS-PAGE (purity > 70%); Western blot with i: anti PM/Scl 100 autoantibody-positive sera; ii: monoclonal anti-hexa-His-tag antibody.
Calculated Molecular Weight
101,644 Dalton
Calculated Isoelectric Point
pH 8.7
Coating Concentration
0.4-0.8 µg/ml (depending on the type of ELISA plate and coating buffer). Suitable for labeling of functional groups.  

A160


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Option Quantity Unit Purchase
PM/Scl100
A16000
0.1 mg
$130.00/EA
In Stock
PM/Scl100
A16001
1.0 mg
$1,505.00/EA
In Stock

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