GP2

Glycoprotein 2 (GP2) is a GPI-anchored protein abundantly produced by the pancreas, but is also expressed on intestinal membranous cells (M-cells), where it serves as a receptor for the phagocytosis of FimH+ Gram-negative bacteria to induce the mucosal immune response. Some results suggest an additional immunosuppressive and anti-inflammatory function of GP2. DIARECT™ antigens are for further manufacturing or research use only.

Origin
Recombinant. Expressed by recombinant baculovirus (Autographa californica multiple nuclear polyhedrosis virus; AcMNPV) infection of Spodoptera frugiperda Sf9 insect cells.
Biochemical Test
SDS-PAGE (purity > 80%); Western blot with i: monoclonal anti-GP2 antibodies; ii: monoclonal anti-hexa-His-tag antibody.
Calculated Molecular Weight
54,909 Dalton
Calculated Isoelectric Point
pH 5.4
Coating Concentration
0.5-0.9 µg/ml (depending on the type of ELISA plate and coating buffer). Suitable for labeling of functional groups.  

A196


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Option Quantity Unit Purchase
GP2
A19600
0.1 mg
$160.00/EA
In Stock
GP2
A19601
1.0 mg
$1,620.00/EA
In Stock

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